AGS Beers Criteria Practice Test

First-generation antihistamines cross into the brain more easily, so they produce sedation plus anticholinergic effects such as dry mouth, blurred vision, and urinary retention. Among these drugs, brompheniramine is known for relatively strong anticholinergic activity, which increases drowsiness and has historically made it a common sleep aid. The other options are typical of newer, second-generation antihistamines that have less penetration into the central nervous system and minimal anticholinergic effects, so they’re not used as sleep aids.